反应详情

温度

120 °C

A pressure-resistant tubular reactor was charged with a mixture of 20.0 g of ethyl 3,3-dimethyl-4-pentenate, 200 g of chloroform and 1.0 g of t-butyl perbenzoate and, after the tube was sealed, the contents were heated at 120° C. for 20 hours. Then, the reaction mixture was distilled to remove the low-boiling fraction and further subjected to distillation under reduced pressure. By the above procedure there were obtained 27.2 g of ethyl β-(3,3,3-trichloropropyl)isovalerate(ethyl 6,6,6-trichloro-3,3-dimethylhexanoate) (yield: 77%).

1. customafter the tube was sealed
2. distillationThen, the reaction mixture was distilled
3. customto remove the low-boiling fraction
4. distillationfurther subjected to distillation under reduced pressure