HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Methyl 2-(dimethylamino)-N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]-2-oxoethanimidothioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Oxamyl | HCID 31657 | — |
| Reactant | Phosphoramidothioic acid, (1-methylethyl)-, O,O-diethyl ester | HCID 778771 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Methyl 2-(dimethylamino)-N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]-2-oxoethanimidothioate | HCID 86739081 | — |
Reaction Steps
Methyl 2-(dimethylamino)-N-[[[[[(diethoxyphosphinothioyl)isopropylamino]sulfinyl]methylamino]carbonyl]oxy]-2-oxoethanimidothioate was prepared by the procedure employed in Example 21, by reacting methyl 2-(dimethylamino)-N-[[(methylamino)carbonyl]oxy]-2-oxoethanimidothioate (3.29 g, 0.015 mole), thionyl chloride (1.79 g, 0.015 mole), and O,O-diethyl isopropylphosphoramidothioate (3.17 g, 0.015 mole) in pyridine (10 ml). Column chromatography afforded 2.6 g of an oil of the formula below, nD24 1.5211 ##STR42##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410518 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-bc98f0a394bd4856a913cc31935e8b76 |
| Source note | uspto-grants-1983_10 |