HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → 4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 9,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one | HCID 12658700 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one | HCID 14209980 | — |
Reaction Steps
From 4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one and phosgene in a mixture of dioxane and toluene, 4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one was obtained;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410527 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-7ea44ece7bb14c26b4b74a7e5ed8485a |
| Source note | uspto-grants-1983_10 |