Fluorobenzene → 5-Ethyl-4-(4-fluorobenzoyl)-2-imidazolidinone

HRID 647833Notes

Reaction equation

HRID 647833 reaction equation
[CH2:1]([CH:3]1[CH:7]([C:8]([OH:10])=O)[NH:6][C:5](=[O:11])[NH:4]1)[CH3:2].[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[CH2:1]([CH:3]1[NH:4][C:5](=[O:11])[NH:6][CH:7]1[C:8](=[O:10])[C:16]1[CH:17]=[CH:18][C:13]([F:12])=[CH:14][CH:15]=1)[CH3:2]

Participants

4

Reactant 2

HCID 10008FluorobenzeneHCID 13245335HCID 13245335, compound

Product 1

HCID 204843625-Ethyl-4-(4-fluorobenzoyl)-2-imidazolidinone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

In 100 g PPA are suspended 15.8 g 4-ethyl-2-oxoimidazolidine-5-carboxylic acid and 10 g fluorobenzene. The mixture is heated to 100° C. for 10 hours with rapid stirring and poured into water. The product separates and is collected.

Workup

  1. customThe product separates and is collected

Sources & evidence

ORD record
ord-4b472cf5cae14116840c266baa3ea072
Source dataset
uspto-grants-1983_10
Patent number
US04410540

Reaction notes

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