反应详情

温度

50 °C

A 11.7 g portion of DL-valine, 13.4 g of N-carbobenzoxy-L-aspartic acid and 2.5 g of sulfuric acid were added to 50 ml of water and the resulting solution was heated to 50° C. This solution was cooled to 20° C. at a rate of 2° C. per hour while stirring, and was stirred for another two hours. The resulting crystal was separated, washed with 20 ml of water and dried to give 9.7 g of an L-valine/N-carbobenzoxy-L-aspartic acid salt. Analysis showed that the optical purity of the L-valine was 98%.

1. temperatureThis solution was cooled to 20° C. at a rate of 2° C. per hour
2. stirringwas stirred for another two hours
3. customThe resulting crystal was separated
4. washwashed with 20 ml of water
5. customdried