反应详情

温度

60 °C

Ten grams of DL-leucine, 12.2 g of N-carbobenzoxy-L-aspartic acid and 1.9 g of sulfuric acid were added to 500 ml of water and the resulting solution was heated to 60° C. This solution was cooled to 10° C. at a rate of 2° C. per hour while stirring, and was stirred for another two hours. The resulting crystal was separated, washed with 30 ml of water and dried to give 9.1 g of an L-leucine/N-carbobenzoxy-L-aspartic acid. Analysis showed that the optical purity of the L-leucine was 95%.

1. temperatureThis solution was cooled to 10° C. at a rate of 2° C. per hour
2. stirringwas stirred for another two hours
3. customThe resulting crystal was separated
4. washwashed with 30 ml of water
5. customdried