1-Propyl-4-piperidone → 1-Methyl-9-propyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

HRID 647929Notes

Reaction equation

HRID 647929 reaction equation
Cl.[NH:2]([C:4]1[CH:5]=[CH:6][C:7]2[S:11][CH:10]=[C:9]([CH3:12])[C:8]=2[CH:13]=1)N.[CH2:14]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH2:19][CH2:18]1)[CH2:15][CH3:16]>>[CH3:12][C:9]1[C:8]2=[C:13]3[C:4](=[CH:5][CH:6]=[C:7]2[S:11][CH:10]=1)[NH:2][C:20]1[CH2:21][CH2:22][N:17]([CH2:14][CH2:15][CH3:16])[CH2:18][C:19]3=1

Participants

3

Reactant 2

HCID 900061-Propyl-4-piperidoneHCID 204843225-Hydrazino-3-methylbenzothiophene hydrochloride

Product 1

HCID 204842911-Methyl-9-propyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

Procedure

The compound is formed analogously to that described in Example 5, from 2.15 g of 5-hydrazino-3-methylbenzothiophene hydrochloride and 1.9 g of 1-propyl-4-piperidone. Melting point: 169° C.

Workup

  1. customThe compound is formed analogously to

Sources & evidence

ORD record
ord-397dbe4d3cac482588e995c962c199f9
Source dataset
uspto-grants-1983_10
Patent number
US04410536

Reaction notes

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