1-(3-Dimethylaminopropyl)-4-piperidone → 9-(3-Dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

HRID 647931Notes

Reaction equation

HRID 647931 reaction equation
Cl.[NH:2]([C:4]1[CH:5]=[CH:6][C:7]2[S:11][CH:10]=[C:9]([CH3:12])[C:8]=2[CH:13]=1)N.[CH3:14][N:15]([CH3:26])[CH2:16][CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][C:22](=O)[CH2:21][CH2:20]1>>[CH3:26][N:15]([CH3:14])[CH2:16][CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][C:22]2[NH:2][C:4]3[C:13]([C:21]=2[CH2:20]1)=[C:8]1[C:9]([CH3:12])=[CH:10][S:11][C:7]1=[CH:6][CH:5]=3

Participants

3

Reactant 2

HCID 180017811-(3-Dimethylaminopropyl)-4-piperidoneHCID 204843225-Hydrazino-3-methylbenzothiophene hydrochloride

Product 1

HCID 204843129-(3-Dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

Procedure

The compound is formed analogously to that described in Example 5, from 5-hydrazino-3-methylbenzothiophene hydrochloride and 8.5 ml of 1-(3-dimethylaminopropyl)-4-piperidone. Melting point: 184° C.

Workup

  1. customThe compound is formed analogously to

Sources & evidence

ORD record
ord-b7c4591f3f46461db18cbcc94f271695
Source dataset
uspto-grants-1983_10
Patent number
US04410536

Reaction notes

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