1-Methyl-4-piperidone → HCID 20484317, compound

HRID 647935Notes

Reaction equation

HRID 647935 reaction equation
Cl.[CH2:2]([C:6]1[C:10]2[CH:11]=[C:12]([NH:15]N)[CH:13]=[CH:14][C:9]=2[S:8][CH:7]=1)[CH2:3][CH2:4][CH3:5].[CH3:17][N:18]1[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]1>C(O)CO>[CH2:2]([C:6]1[C:10]2=[C:11]3[C:12](=[CH:13][CH:14]=[C:9]2[S:8][CH:7]=1)[NH:15][C:21]1[CH2:22][CH2:23][N:18]([CH3:17])[CH2:19][C:20]3=1)[CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 20484281HCID 20484281, compound

Product 1

HCID 20484317HCID 20484317, compound

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Conditions

Temperature
100 °C

Procedure

The compound is formed analogously to that described in Example 5, from 25.6 g of 3-butyl-5-hydrazinobenzothiophene hydrochloride and 13.5 g of 1-methyl-4-piperidone in ethylene glycol, the mixture being heated to 100° C. for 30 minutes and then to 180° C. Melting point: 192°-193° C.

Workup

  1. customThe compound is formed analogously to
  2. customto 180° C

Sources & evidence

ORD record
ord-11fd86ddb7ba42bbad9c1e82f8c752e7
Source dataset
uspto-grants-1983_10
Patent number
US04410536

Reaction notes

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