1-(Isopropyl)-4-piperidone → 9-Isopropyl-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

HRID 647937Notes

Reaction equation

HRID 647937 reaction equation
Cl.[NH:2]([C:4]1[CH:5]=[CH:6][C:7]2[S:11][CH:10]=[C:9]([CH3:12])[C:8]=2[CH:13]=1)N.[CH:14]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH2:19][CH2:18]1)([CH3:16])[CH3:15]>>[CH:14]([N:17]1[CH2:22][CH2:21][C:20]2[NH:2][C:4]3[C:13]([C:19]=2[CH2:18]1)=[C:8]1[C:9]([CH3:12])=[CH:10][S:11][C:7]1=[CH:6][CH:5]=3)([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 793131-(Isopropyl)-4-piperidoneHCID 204843225-Hydrazino-3-methylbenzothiophene hydrochloride

Product 1

HCID 204842869-Isopropyl-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole

Procedure

The compound is formed analogously to that described in Example 15, from 11 g of 5-hydrazino-3-methylbenzothiophene hydrochloride and 10 g of 1-isopropyl-4-piperidone. Melting point: 199°-203° C.

Workup

  1. customThe compound is formed analogously to that

Sources & evidence

ORD record
ord-d6ad2ab196ea45b988b43459d7d7dae2
Source dataset
uspto-grants-1983_10
Patent number
US04410536

Reaction notes

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