1-Benzyl-4-piperidone → HCID 20484280, compound
Reaction equation
Cl.[CH2:2]([C:6]1[C:10]2[CH:11]=[C:12]([NH:15]N)[CH:13]=[CH:14][C:9]=2[S:8][CH:7]=1)[CH2:3][CH2:4][CH3:5].[CH2:17]([N:24]1[CH2:29][CH2:28][C:27](=O)[CH2:26][CH2:25]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:2]([C:6]1[C:10]2=[C:11]3[C:12](=[CH:13][CH:14]=[C:9]2[S:8][CH:7]=1)[NH:15][C:27]1[CH2:28][CH2:29][N:24]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:25][C:26]3=1)[CH2:3][CH2:4][CH3:5]Participants
3
Procedure
The compound is formed analogously to that described in Example 5, from 25.6 g of 3-butyl-5-hydrazinobenzothiophene hydrochloride and 23 g of 1-benzyl-4-piperidone. Melting point: 127°-128° C.
Workup
- customThe compound is formed analogously to
Sources & evidence
- ORD record
- ord-18c9bdb793c645e1a06382750d12f7f2
- Source dataset
- uspto-grants-1983_10
- Patent number
- US04410536
Reaction notes
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