1-Ethylpiperidin-4-one → HCID 20484300, compound

HRID 647950Notes

Reaction equation

HRID 647950 reaction equation
Cl.[CH2:2]([C:4]1[C:8]2[CH:9]=[C:10]([NH:13]N)[CH:11]=[CH:12][C:7]=2[S:6][CH:5]=1)[CH3:3].[CH2:15]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH2:19][CH2:18]1)[CH3:16]>C(O)CO>[CH2:2]([C:4]1[C:8]2=[C:9]3[C:10](=[CH:11][CH:12]=[C:7]2[S:6][CH:5]=1)[NH:13][C:20]1[CH2:21][CH2:22][N:17]([CH2:15][CH3:16])[CH2:18][C:19]3=1)[CH3:3]

Participants

4

Reactant 2

HCID 771591-Ethylpiperidin-4-oneHCID 20484335HCID 20484335, compound

Product 1

HCID 20484300HCID 20484300, compound

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

The compound is formed analogously to that described in Example 36, from 8.0 g of 3-ethyl-5-hydrazinobenzothiophene hydrochloride and 6.0 g of 1-ethyl-4-piperidone, by cyclisation under the influence of heat at 165°-170° C. in ethylene glycol for 3 hours.

Workup

  1. customThe compound is formed analogously to that

Sources & evidence

ORD record
ord-21cfc54048b34f6e85c313e621ccabbb
Source dataset
uspto-grants-1983_10
Patent number
US04410536

Reaction notes

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