1-(Benzylamino)-3-[(3-methylpyridin-2-yl)oxy]propan-2-ol → 1-Amino-3-[(3-methylpyridin-2-yl)oxy]propan-2-ol

Participants

Reaction Steps

Catalytic debenzylation of a solution of 28.3 g of 2-(3'-benzylamino-2'-hydroxy-propoxy)-3-methyl-pyridine in 300 ml of ethyl acetate, with the addition of a total of 12 g of palladium on charcoal (5% strength), gives 2-(3'-amino-2'-hydroxy-propoxy)-3-methylpyridine of boiling point 120°-130° C./0.07 mm Hg in a bulb tube.

Provenance & Evidence