Pyrrole-2-carbonyl chloride → HCID 20456522, compound

HRID 647993Notes

Reaction equation

HRID 647993 reaction equation
N1C=[CH:4][CH:3]=[C:2]1[C:6](Cl)=O.[CH3:9][N:10]([CH3:18])[C:11]([C:13]1[NH:14][CH:15]=[CH:16][CH:17]=1)=[O:12]>>[CH3:9][N:10]([CH3:18])[C:11]([C:13]1[N:14]([CH2:6][CH2:2][CH2:3][CH3:4])[CH:15]=[CH:16][CH:17]=1)=[O:12]

Participants

3

Reactant 2

HCID 224558Pyrrole-2-carbonyl chlorideHCID 11073495N,N-dimethyl-1H-pyrrole-2-carboxamide

Product 1

HCID 20456522HCID 20456522, compound

Procedure

Likewise, by the method of part B of this Preparation, pyrrole-2-carbonyl chloride, obtained as described by R. J. Boatman et al., in J. Org. Chem. 41, p. 3050 (1976), is converted into N,N-dimethylpyrrole-2-carbox-amide, m.p. 100.5°-102° C.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-12e5e78cb3ba4a5b948dd483b5f9cac3
Source dataset
uspto-grants-1983_10
Patent number
US04410534

Reaction notes

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