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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 648012Generated: October 29, 2026

4,N,N-Trimethylbenzamide → Isopropyl 3-p-toluoyl-2-methyl-5,6,7,8-tetrahydropyrrolo[1,2-a]pyridine-8-carboxylate

https://huagongshe.com/reaction/648012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,N,N-TrimethylbenzamideHCID 84179—
Reactantisopropyl 2-methyl-6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]azepine-9-carboxylateHCID 20483821—
ProductIsopropyl 3-p-toluoyl-2-methyl-5,6,7,8-tetrahydropyrrolo[1,2-a]pyridine-8-carboxylateHCID 20483828—

Reaction Steps

In like manner, condensing isopropyl 2-methyl-6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]azepine-9-carboxylate with N,N-dimethyl-p-toluamide there is obtained isopropyl 5-p-toluoyl-2-methyl-6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]azepine-1-carboxylate (XI, R=CH3, L=p-CHR=iC3H72, n=2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04410534
Source datasetuspto-grants-1983_10
ORD IDord-939bc47b464c4773a786f10d5b456277
Source noteuspto-grants-1983_10