Diazomethane → HCID 20483787, compound

Participants

Reaction Steps

A solution of 269 mg. of 3-benzoyl-5,6,7,8-tetrahydropyrrolo[1,2-a]pyridine-8-carboxylic acid in 10 ml. of dichloromethane is treated with an excess of ethereal diazomethane, and the reaction mixture is maintained at room temperature for 30 minutes. The solvents and excess reagent are eliminated under reduced pressure and the residue crystallized from ethyl acetate-methanol, to yield methyl 3-benzoyl-5,6,7,8-tetrahydropyrrolo[1,2-a]pyridine-8-carboxylate.

Provenance & Evidence