HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 13662981, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 5-methyl-1-benzothiophene-2-carboxylate | HCID 13662971 | — |
| Catalyst | Azobisisobutyronitrile | HCID 6547 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 13662981 | HCID 13662981 | 97.4% |
Reaction Steps
A mixture of 5-methylbenzo[b]thiophene-2-carboxylic acid methyl ester (3.09 g.), N-bromosuccinimide (2.67 g.) and azobisisobutyronitrile (0.20 g.) in carbon tetrachloride (150 ml.) was heated under reflux for 5 hours. The mixture was then filtered and the filtrate was evaporated to give a solid which was crystallized from methanol to give 5-bromomethylbenzo[b]thiophene-2-carboxylic acid methyl ester (4.16 g.), m.p. 108°-110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410539 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-6184cf64deba45759ccb5b676b87db5d |
| Source note | uspto-grants-1983_10 |