Hydrogen Peroxide → HCID 12811402, compound

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Reaction Steps

10% v/v Aqueous hydrogen peroxide (27 ml) was added to 2-methoxy-5-methyl-4-(methylthio)phenol (1.72 g) in glacial acetic acid (15 ml). After 24 hours the acetic acid was neutralised with 2 N aqueous sodium hydroxide and the product was extracted into methylene chloride (100 ml). The organic extract was washed with 10% w/v aqueous sodium sulphite solution and water, dried (Na2SO4) and the solvent was removed in vacuo. Recrystallisation from ethanol/diethyl ether gave 2-methoxy-5-methyl-4-methylsulphinylphenol (0.16 g) as colourless crystals m.p. 166°-168° (identical to that prepared in (i) above).

Provenance & Evidence