HCID 20484847, compound → HCID 131712552, compound

Participants

Reaction Steps

A mixture of a solution of the compound of Example 1 in ethyl acetate and 90 mg of 5% palladized carbon were placed in a hydrogenation apparatus and the mixture was stirred under a slight hydrogen pressure for 30 minutes. The mixture was filtered and the filtrate was evaporated to dryness. The residue was chromatographed over silica gel and was eluted with a 3-7 ether-hexane mixture to obtain 275 mg of ethyl cis 2,2-dimethyl-3-(2-hydroxy-2-methyl-propyl)-cyclopropane-1-carboxylate.

Provenance & Evidence