HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Diclofenac
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,6-Dichloroaniline | HCID 11846 | — |
| Reactant | HCID 23666463 | HCID 23666463 | — |
| Reactant | HCID 23715416 | HCID 23715416 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Diclofenac | HCID 3033 | — |
Reaction Steps
The same procedure as in Example 1 given in Japanese Pat. No. 374/1980 was employed using 3.10 g of 2,6-dichloroaniline, 0.10 g of cuprous bromide, 2.80 g of potassium carbonate and 10 ml of dimethyl sulfoxide except that potassium o-bromophenylacetate was replaced with 4.17 g of potassium o-chlorophenylacetate. o-(2,6-Dichloroanilino)phenylacetic acid was not obtained at all.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410724 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-a312f77bdebf4db4b750b44d12a73245 |
| Source note | uspto-grants-1983_10 |