Hydrogen Bromide → HCID 12902573, compound

Participants

Reaction Steps

Six milliliters of 47% hydrobromic acid was added to 0.51 g of methyl 11-methoxy-5H-dibenzo[a,d]cycloheptene-2-acetate obtained in Example 12, and the mixture was stirred at room temperature for 2 hours. After the reaction, water was added to the reaction mixture, and the mixture was extracted with ether. The ethereal layer was washed with a saturated aqueous solution of sodium chloride, and the ether was distilled off. Recrystallization of the residue from n-hexane afforded 0.43 g of methyl 10,11-dihydro-11-oxo-5H-dibenzo[a,d]cycloheptene-2-acetate as colorless needle-like crystals having a melting point of 111° to 112° C.

Provenance & Evidence