Water → Benzamide

HRID 648135Notes

Reaction equation

HRID 648135 reaction equation
[C:1](#[N:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH2:9]>[O-2].[Cr+3].[Cu+2]>[C:1]([NH2:8])(=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 962WaterHCID 7505Benzonitrile2×

Product 1

HCID 2331BenzamideYield 20%

Reagents, catalysts & solvents 1

HCID 131711404Copper-chromium oxideCatalyst

Procedure

Watanabe et al., in Bull. Chem. Soc. Japan, 39, 8 (1966) also show the use of a copper chromium oxide catalyst, Cu--CrO2, to convert benzonitrile to benazmide. Although the preparation is not disclosed, Watanabe's catalyst apparently was not prepared according to the present invention since benzonitrile in water reacted in the presence of the catalyst for 8 hours gave only a 20% yield of benzamide.

Workup

  1. customWatanabe's catalyst apparently was not prepared
  2. customreacted in the presence of the catalyst for 8 hours

Sources & evidence

ORD record
ord-dc2244ca1787420599fd07c78be8797e
Source dataset
uspto-grants-1983_10
Patent number
USRE031430

Reaction notes

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