反应详情

Four grams (18.9 mmol) of α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide is dissolved in hot ethanol/toluene. To this is added, portionwise, 4 g of 2,4,6-trichlorophenylhydrazine. The mixture is heated to reflux for three days. Cooling of the mixture and evaporation of the solvent gives the crude product, which is recrystallized from ethanol (3 X) to yield α-cyano-β-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide, m.p. =161° (dec.).

1. additionTo this is added
2. temperatureThe mixture is heated
3. temperatureto reflux for three days
4. temperatureCooling of the mixture and evaporation of the solvent
5. customgives the crude product, which
6. customis recrystallized from ethanol (3 X)