Dimethyl Sulfate → HCID 20459812, compound

Participants

Reaction Steps

To a mixture of 5-cyano-1-(2,6-dimethylanilino)-2,4-pyrimidinedione (0.1 mol) and 80 ml of 5% sodium hydroxide solution, with stirring, is slowly added dimethyl sulfate (0.1 mol). The reaction mixture is stirred for about 2-4 hours and then filtered, washed with water and dried to yield 5-cyano-1-(2,6-dimethylanilino)-3-methyl-2,4-pyrimidinedione.

Provenance & Evidence