Tetrafluoroboric acid → HCID 13326266, compound

Participants

Reaction Steps

Sodium nitrite (1.1 mole) dissolved in water is slowly added to a cool (0°-5°) solution of 6-amino-1-(2,6-dimethylanilino)-2,4-pyrimidinedione (1 mole) in dilute fluoboric acid. The precipitate which forms is filtered off, washed with water, dried and pyrolyzed under nitrogen (only a small amount at a time) to give 6-fluoro-1-(2,6-dimethylanilino)-2,4-pyrimidinedione.

Provenance & Evidence