HCID 13069221, compound → HCID 13069203, compound

Participants

Reaction Steps

As described in Example 9(a), 4.6 g of 5-(2,4-difluorophenoxy)-4-nitrophthalic acid in 20 ml of absolute tetrahydrofuran is reduced with 100 ml of a 0.3-molar borane-tetrahydrofuran complex solution in tetrahydrofuran and worked up. Crystallization from ethanol yields 1.3 g of 6-(2,4-difluorophenoxy)-5-nitrophthalide, mp 164°-165.5° C.

Provenance & Evidence