2-Bromoisovaleric acid → HCID 54407243, compound

HRID 648259Notes

Reaction equation

HRID 648259 reaction equation
Br[CH:2]([CH:6]([CH3:8])[CH3:7])[C:3]([OH:5])=[O:4].[Cl:9][C:10]1[CH:16]=[C:15]([CH3:17])[CH:14]=[CH:13][C:11]=1[NH2:12].O(C1C=C(C=CC=1)CBr)C1C=CC=CC=1>>[Cl:9][C:10]1[CH:16]=[C:15]([CH3:17])[CH:14]=[CH:13][C:11]=1[NH:12][C@H:2]([C:3]([OH:5])=[O:4])[CH:6]([CH3:8])[CH3:7]

Participants

4

Reactant 3

HCID 112682-Bromoisovaleric acidHCID 120072-Chloro-p-toluidineHCID 945441-(Bromomethyl)-3-phenoxybenzene

Product 1

HCID 54407243HCID 54407243, compound

Procedure

N-(2-chloro-4-methylphenyl)valine is prepared as above from α-bromoisovaleric acid and 2-chloro-4-methylaniline and then reacted with m-phenoxybenzyl bromide, as above, to yield the m-phenoxybenzyl ester of N-(2-chloro-4-methylphenyl)valine. MS m/e 423 (M+, 4), 196 (100).

Sources & evidence

ORD record
ord-821a3a0c327740b29b871989257bd548
Source dataset
uspto-grants-1983_10
Patent number
US04411912

Reaction notes

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