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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 648280Generated: October 30, 2026

4-(Trifluoromethyl)aniline → Valine, N-[4-(trifluoromethyl)phenyl]-

https://huagongshe.com/reaction/648280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)anilineHCID 9964—
Reactantalpha-Cyano-m-phenoxybenzyl alpha-bromoisovalerateHCID 13705788—
ProductValine, N-[4-(trifluoromethyl)phenyl]-HCID 13388454—

Reaction Steps

Following the procedure of Example 6, 4-trifluoromethylaniline is reacted with α-cyano-m-phenoxybenzyl α-bromoisovalerate to yield the α-cyano-m-phenoxybenzyl ester of N-(4-trifluoromethylphenyl)valine, MS m/e 468.2 (M+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04411912
Source datasetuspto-grants-1983_10
ORD IDord-43dc9802ea724a8084d1490354e8d8ee
Source noteuspto-grants-1983_10