4-(Trifluoromethylthio)nitrobenzene → 4-((Trifluoromethyl)thio)aniline

Participants

Reaction Steps

To p-nitrophenyl trifluoromethyl sulfide (3.0 g) in absolute ethanol (30 ml) is added Adams catalyst (Pt2O, 0.026 g). The mixture is hydrogenated in a Parr vessel at 50 lbs/sq. in. for about 15 min. The reaction is worked up by filtering through Celite and evaporating to yield p-aminophenyl trifluoromethyl sulfide.

Provenance & Evidence