HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzocaine → Ethyl 4-(11-bromoundecanamido)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzocaine | HCID 2337 | — |
| Reactant | Undecanoyl chloride, 11-bromo- | HCID 85202 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethyl 4-(11-bromoundecanamido)benzoate | HCID 20482534 | — |
Reaction Steps
A solution of 28 g. of 11-bromoundecanoyl chloride in 100 ml. of methylene chloride is slowly added with stirring to a solution of 20 g. of ethyl 4-aminobenzoate in 100 ml. of methylene chloride. The mixture is filtered and the filtrate is washed with dilute hydrochloric acid and water, dried, and evaporated. Crystallization from acetonitrile affords ethyl 4-(11-bromoundecanamido)benzoate as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04411903 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-20f34d8549964dabaceca69620caa7f5 |
| Source note | uspto-grants-1983_10 |