Ethyl 2-(2,3-dihydro-1,4-dithiin-6-yl)-2-methoxyiminoacetate → 2-Methoxyimino-2-(2,3-dihydro-1,4-dithiin-5-yl)acetic acid

HRID 648400Notes

Reaction equation

HRID 648400 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:10]1[S:11][CH2:12][CH2:13][S:14][CH:15]=1)[C:5]([O:7]CC)=[O:6]>[OH-].[Na+]>[CH3:1][O:2][N:3]=[C:4]([C:10]1[S:11][CH2:12][CH2:13][S:14][CH:15]=1)[C:5]([OH:7])=[O:6]

Participants

3

Reactant 1

HCID 54260118Ethyl 2-(2,3-dihydro-1,4-dithiin-6-yl)-2-methoxyiminoacetate

Product 1

HCID 539358522-Methoxyimino-2-(2,3-dihydro-1,4-dithiin-5-yl)acetic acidYield 91.3%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Ethyl 2-methoxyimino-2-(2,3-dihydro-1,4-dithiin-5-yl)acetate (syn isomer) (2.47 g) was treated with 1 N aqueous solution of sodium hydroxide (20 ml.) according to similar manners to those of Examples 1 (a) (5), 2 (a) (3) and 3(a) (3) to give 2-methoxyimino-2-(2,3-dihydro-1,4-dithiin-5-yl)acetic acid (syn isomer) (2.0 g.), mp. 120° to 122° C. (dec.).

Sources & evidence

ORD record
ord-cb3e44de4a254779910a9533e1d98742
Source dataset
uspto-grants-1983_10
Patent number
US04411898

Reaction notes

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