反应详情

To a solution of 3.99 g (18.8 mmoles) (2) in 30 ml ether under nitrogen was added 1.49 g (18.8 mmoles) pyridine. A white precipitate formed and the mixture was stirred overnight. The precipitate was then filtered off, washed with ether, and dried to give 3.64 g (66%) 4-(2,1-benzisoxazolyl)methylpyridinium bromide, m.p. 172°-174°; nmr (DMSO-d6): 6.3 (s, 2H), 7.5 (m, 3H), 8.2 (m, 2H), 8.9 (m, 1H), 9.6 (dd, 2H), 10.3 (s, 1H).

1. customA white precipitate formed
2. filtrationThe precipitate was then filtered off
3. washwashed with ether
4. customdried