Isopropanol → HCID 14098294, compound

Participants

Reaction Steps

To 0.58 g (4 mmol) 3-formylimidazo[1,5-a]pyridine (1) in 15 ml isopropanol was added 0.46 g (4 mmol) methyl 3-aminocrotonate and 0.46 g (4 mmol) methyl acetoacetate and the resulting solution was heated at reflux for 20 hours. The cooled reaction mixture was then filtered to give a yellow solid which was washed with ether and subsequently recrystallized from methanol to give pure (2), m.p. 255°-257° (dec).

Provenance & Evidence