Butyric Acid → Propyl butyrate

HRID 648470Notes

Reaction equation

HRID 648470 reaction equation
O[C:2]1[C:11]2C(=C(C(F)(F)F)C=CC=2)N=C(C(O)CC)[C:3]=1C(NC1SC=CN=1)=O.[C:28]([OH:33])(=[O:32])[CH2:29][CH2:30][CH3:31]>>[C:28]([O:33][CH2:3][CH2:2][CH3:11])(=[O:32])[CH2:29][CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 264Butyric AcidHCID 178458925HCID 178458925, compound

Product 1

HCID 7770Propyl butyrate

Procedure

Using the procedure of Example 5, 8 g of 4-hydroxy-2-(1-hydroxypropyl)-N-(2-thiazolyl)-8-trifluoromethyl-3-quinoline carboxamide and 2 ml of butyric acid were reacted to obtain 7.8 g of 1-[4-hydroxy-3-[(2-thiazolylamino)-carboxyl]-8-trifluoromethyl)-2-quinolinyl]-propyl butanoate melting at 203° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-4402c38642f04e6b8a567dcedc3325e4
Source dataset
uspto-grants-1988_04
Patent number
US04735951

Reaction notes

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