4-Chlorobenzenesulfonyl chloride → 4-Chloro-N-[5-(1H-imidazol-1-yl)pentyl]benzenesulfonamide hydrochloride

HRID 64856Notes

Reaction equation

HRID 64856 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:5]=[CH:4][N:3]=[CH:2]1.[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>>[ClH:12].[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([S:19]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][N:1]2[CH:5]=[CH:4][N:3]=[CH:2]2)(=[O:21])=[O:20])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 71384341H-Imidazole-1-pentanamine

Product 1

HCID 202357704-Chloro-N-[5-(1H-imidazol-1-yl)pentyl]benzenesulfonamide hydrochloride

Procedure

The compound of this Example, mp 157°-161° C., was obtained when 1H-imidazole-1-pentanamine was reacted with 4-chlorobenzenesulfonyl chloride by the procedure of Example 20.

Sources & evidence

ORD record
ord-9d5fa40859af4f53bbb6d26703ff9d04
Source dataset
uspto-grants-1986_09
Patent number
US04610981

Reaction notes

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