Sodium Carbonate → HCID 20145227, compound

HRID 648637Notes

Reaction equation

HRID 648637 reaction equation
[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([CH:15]([C:36]([NH2:38])=[O:37])[C:16]2[CH:35]=[CH:34][C:19]([C:20](NNS(C3C=CC(C)=CC=3)(=O)=O)=[O:21])=[CH:18][CH:17]=2)[CH3:14])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(=O)([O-])[O-].[Na+].[Na+]>C(O)CO>[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([CH:15]([C:36]([NH2:38])=[O:37])[C:16]2[CH:17]=[CH:18][C:19]([CH:20]=[O:21])=[CH:34][CH:35]=2)[CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 10340Sodium CarbonateHCID 86742088HCID 86742088, compound

Product 1

HCID 20145227HCID 20145227, compound

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

The above compound was prepared by the heating of crude N1 -[4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]benzoyl]-N2 -tosyl-hydrazine with anhydrous sodium carbonate at 160°-170° C. in ethylene glycol [prepared from 4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid and tosyl-hydrazine with carbonyl diimidazole in tetrahydrofuran].

Workup

  1. customThe above compound was prepared by the

Sources & evidence

ORD record
ord-8b3b296493e4403e8ce56ba4fb60b574
Source dataset
uspto-grants-1988_04
Patent number
US04735959

Reaction notes

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