4-Cyanophenylacetic acid → HCID 20145180, compound

HRID 648653Notes

Reaction equation

HRID 648653 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH2:21])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[N:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)=[CH:4][CH:3]=1.[C:22]([C:24]1[CH:29]=[CH:28][C:27]([CH2:30][C:31](O)=[O:32])=[CH:26][CH:25]=1)#[N:23]>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([NH:21][C:31]([CH2:30][C:27]2[CH:28]=[CH:29][C:24]([C:22]#[N:23])=[CH:25][CH:26]=2)=[O:32])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[N:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 795874-Cyanophenylacetic acidHCID 13281037HCID 13281037, compound

Product 1

HCID 20145180HCID 20145180, compound

Procedure

Prepared from α-(4-methyl-phenyl)-2-piperidino-benzylamine and 4-cyano-phenylacetic acid analogously to Example 55.

Sources & evidence

ORD record
ord-274aba8513be4a32a3493d1136a581a1
Source dataset
uspto-grants-1988_04
Patent number
US04735959

Reaction notes

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