Sulfuric Acid → HCID 20145118, compound

HRID 648656Notes

Reaction equation

HRID 648656 reaction equation
[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13](O)[CH2:14][CH2:15][CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:18]([CH2:20][C:21]1[CH:31]=[CH:30][C:24]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:23][CH:22]=1)#[N:19].S(=O)(=O)(O)[OH:33]>ClC1C=CC=CC=1Cl>[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([CH:20]([C:18]([NH2:19])=[O:33])[C:21]2[CH:31]=[CH:30][C:24]([C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:23][CH:22]=2)[CH2:14][CH2:15][CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 11989373ethyl 4-(cyanomethyl)benzoateHCID 21261884HCID 21261884, compound

Product 1

HCID 20145118HCID 20145118, compound

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Procedure

Prepared analogously to Example 64 from 1-(2-piperidinophenyl)-1-butanol and ethyl 4-cyanomethyl-benzoate with concentrated sulfuric acid in o-dichlorobenzene at ambient temperature.

Sources & evidence

ORD record
ord-6a535e93b4d141d99bb40177a415238f
Source dataset
uspto-grants-1988_04
Patent number
US04735959

Reaction notes

Loading…