HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 4-(4-Chlorobenzoyl)-piperazin-1-yl-acetic acid morpholide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 2-Chlorobenzoyl chloride | HCID 69110 | — |
| Reactant | 1-(Morpholinocarbonylmethyl)piperazine | HCID 100622 | — |
| Product | 4-(4-Chlorobenzoyl)-piperazin-1-yl-acetic acid morpholide hydrochloride | HCID 86740986 | — |
Reaction Steps
5 g of piperazinoacetic acid morpholide and 4.2 g of chlorobenzoyl chloride are brought together in 50 ml of methylene chloride at 0° C. The mixture is stirred at room temperature for 2 hours and cooled again to 0° C., whereupon a precipitate separates out, and is recrystallised from isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04610984 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-00c9c449b98d467ca6ce6714565bfd2c |
| Source note | uspto-grants-1986_09 |