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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 648712Generated: October 26, 2026

6-Chloropicolinic acid → 6-chloropyridine-2-carbonyl Chloride

https://huagongshe.com/reaction/648712

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloropicolinic acidHCID 20812—
ReactantThionyl ChlorideHCID 24386—
Product6-chloropyridine-2-carbonyl ChlorideHCID 10942976—

Reaction Steps

A mixture of 40 g 6-chloro-2-pyridinecarboxylic acid and 150 ml SOCl2 is refluxed 4 hrs. After removing excess SOCl2 there is obtained 44 g 6-chloro-2-pyridinecarboxylic acid chloride, m.p. 76° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04736037
Source datasetuspto-grants-1988_04
ORD IDord-33a5c562a1eb40ec88fa88f5c8b6de44
Source noteuspto-grants-1988_04