HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 6-Bromo-2-(2-methoxybenzoyl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 6-Bromo-alpha-(2-methoxyphenyl)-2-pyridinemethanol | HCID 20145729 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-Bromo-2-(2-methoxybenzoyl)-pyridine | HCID 20145716 | 66.2% |
Reaction Steps
By the same procedure of Ex. 22, and reacting 3.3 g 6-bromo-α-(2-methoxyphenyl)-2-pyridinemethanol (obtained as in Ex. 19) in 20 ml glacial acetic acid with CrO3 (1 g in 5 ml water), there is obtained 2.17 g title product, m.p. 97°-8° C. (ethanol:water); UV (ethanol): λmax. 278 nm, ε: 12,480; Br 27.67 (27.36).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04736037 |
| Source dataset | uspto-grants-1988_04 |
| ORD ID | ord-c202bd4e9b43463a8906d1e99955bab8 |
| Source note | uspto-grants-1988_04 |