Sodium Hydroxide → alpha-(4-Hydroxybenzenesulfonyloxyimino)benzyl cyanide

Participants

Reaction Steps

14.6 g (0.1 mole) of α-hydroxyiminobenzyl cynide (1c) are reacted with 23.46 g (0.1 mole) of 4-acetoxybenzenesulfonyl chloride (3a) in accordance with a procedure analogous to that of Example 3c. The resultant α-(4-acetoxybenzenesulfonyloxyimino)benzyl cyanide melts at 142°-143° C. 6 g of this compound are hydrolysed with a solution of NaOH in accordance with a procedure analogous to that of Example 3d, affording the title compound which, after recrystalisation from toluene, melts at 148° C.

Provenance & Evidence