Epichlorohydrin → HCID 88638245, compound

Participants

Reaction Steps

20 g (0.057 moles) of mono2-hexyldecyl phosphate having a purity of 92% (AV1=167.2, AV2=329.8) was dispersed in 59.6 ml of 1N sodium hydroxide aqueous solution, at which the acid value of the reaction system was 39.5. While keeping the reaction system at 80° C., 16.5 g (0.178 moles) of epichlorohydrin was gradually added, followed by agitation at the temperature for 8 hours. The acid value of the reaction system was approximately zero, revealing that the conversion rate of the phosphoric monoester was almost 100%. The reaction solution was analyzed by HPLC. The chromatography showed peaks corresponding to hydrolysate or epichlorhidrine and a new reaction product. The resulting product was collected by HPLC and the solvent was distilled off under reduced pressure to obtain 20.5 g (yield 82.3%) of sodium 2-hexyldecyl 2-hydroxy-3-chloropropyl phosphate.

Provenance & Evidence