1,2-Dibromoethane → HCID 14150221, compound

Participants

Reaction Steps

In a manner similar to the procedure described in Example B except that a one liter three-necked Morton flask was used, 39.0 grams (0.14 mol) of ethyl 3-[(2,4-dichlorophenyl)amino]-3-oxopropanoate, 53.9 grams (0.39 mol) of anhydrous potassium carbonate, 125 milliliters of anhydrous dimethylformamide and 13.4 milliliters (0.16 mol) of 1,2-dibromoethane were reacted for a period of 65 hours to give 35.3 grams (0.117 mol) of ethyl 1-(2,4-dichlorophenylaminocarbonyl)cyclopropanecarboxylate as a pale yellow solid having a melting point of 95.0° C.-96.0° C. The total yield was 83 percent. NMR analysis of the product indicated the following:

Provenance & Evidence