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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 64887Generated: October 26, 2026

4-Chloropyridine hydrochloride → 5-Methoxy-2-(4-pyridinylamino)benzoic acid

https://huagongshe.com/reaction/64887

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyridine hydrochlorideHCID 81852—
Reactant5-Methoxyanthranilic acidHCID 277930—
Product5-Methoxy-2-(4-pyridinylamino)benzoic acidHCID 20235853111.7%

Reaction Steps

5-Methoxy-2-(4-pyridinylamino)benzoic acid was prepared from 4.9 g of 5-methoxyanthranilic acid and 4.4 g of 4-chloropyridine hydrochloride according to the procedure of Example 1, part (a). There was obtained 8.0 g of 5-methoxy-2-(4-pyridinylamino)benzoic acid which was recrystallized from water and used directly in the next reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04610991
Source datasetuspto-grants-1986_09
ORD IDord-3dc619b6ebe644b1beae46073ca5a95e
Source noteuspto-grants-1986_09