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HRID648877

反应详情

EQUATION

反应方程式

HRID 648877 的结构方程式

REACTANTS

反应物

3
结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：CCCCCCC(C)OS(=O)(=O)c1ccc(C)cc1
HCID3912199

未命名化合物

结构：CC(=O)c1ccc(-c2ccc(O)c(F)c2)cc1
HCID14388649

1-(3'-Fluoro-4'-hydroxy[1,1'-biphenyl]-4-yl)ethan-1-one

C14H11FO2

PRODUCTS

生成物

1
结构：CCCCCCC(C)Oc1ccc(-c2ccc(C(C)=O)cc2)cc1F
HCID14388650

未命名化合物

收率 28.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

3'-Fluoro-4'-hydroxy-4-acetylbiphenyl (15 g), potassium hydroxide (4.0 g), ethanol (370 ml), optically active 1-methylheptyl p-toluenesulfonate (20.5 g), were heated for 5 hrs. under reflux, to obtain by usual work-up, 6.37 g of 3'-fluoro-4'-(1-methylheptyloxy)-4-acetylbiphenyl, m.p. 67.6°~68.5° C.

WORKUP

后处理

  1. temperatureunder reflux