Decanoyl chloride → HCID 54192954, compound

Participants

Reaction Steps

To 21.0 g (0.1 mole) of pulverized α-pyridoin (commercially available, e.g. from Aldrich Chemical Co.) was added 9.5 g (0.05 mole) decanoyl chloride. The reaction mixture was mixed for 30 minutes, after which it became solid. The solid was extracted with acetonitrile and the acetonitrile solution evaporated to yield an oily semisolid. Recrystallization from 70% cyclohexanone-30% acetone yielded 1.3 g (9.9%) white fine needles of compound NA-IV, m.p. 89°-90° C.

Provenance & Evidence