反应详情

温度

120 °C

A mixture of 13.2 g of (4-carboethoxyphenyl)thiosemicarbazide, 52.8 ml of ethyl orthoformate, and 3.3 g of acetic acid was stirred for 2 hours at 120° C. After cooling the mixture to room temperature, hexane was added to the mixture and crystals thus formed were collected by filtration and recrystallized from ethanol to provide 10.4 g of 1-(4-carboethoxyphenyl)-2-mercapto-1,3,4-triazole. The yield was 75.9% and the melting point was 194°-196° C.

1. temperatureAfter cooling the mixture to room temperature
2. customthus formed
3. filtrationwere collected by filtration
4. customrecrystallized from ethanol