HCID 13474248, compound → HCID 14100462, compound

HRID 648936Notes

Reaction equation

HRID 648936 reaction equation
[S:1]1[CH2:6][CH2:5][N:4]([CH2:7][N:8]2[C:13](=[O:14])[CH2:12][N:11]([CH2:15][CH:16]([N:18]3[CH2:23][C:22](=[O:24])[N:21](CN4CCSCC4)[C:20](=[O:32])[CH2:19]3)[CH3:17])[CH2:10][C:9]2=[O:33])[CH2:3][CH2:2]1>O>[S:1]1[CH2:6][CH2:5][N:4]([CH2:7][N:8]2[C:13](=[O:14])[CH2:12][N:11]([CH2:15][CH:16]([N:18]3[CH2:19][C:20](=[O:32])[NH:21][C:22](=[O:24])[CH2:23]3)[CH3:17])[CH2:10][C:9]2=[O:33])[CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 13474248HCID 13474248, compound

Product 1

HCID 14100462HCID 14100462, compoundYield 43.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Water (30 ml) was added to dl-1,2-bis(4-thiomorpholinomethyl-3,5-dioxopiperazin-1-yl)-propane (0.6 g) and the suspension thus obtained was stirred at room temperature for 5 hours. Then, the precipitates thus obtained were collected and were dried under a reduced pressure. Chloroform (10 ml) was added to the dried precipitates and the whole was stirred at room temperature for 20 minutes, then was filtered. The filtration residue was dried under a reduced pressure to give the titled compound (0.2 g; yield 43%).

Workup

  1. customthe suspension thus obtained
  2. customThen, the precipitates thus
  3. customobtained
  4. customwere collected
  5. customwere dried under a reduced pressure
  6. additionChloroform (10 ml) was added to the dried
  7. customprecipitates
  8. stirringthe whole was stirred at room temperature for 20 minutes
  9. filtrationwas filtered
  10. customThe filtration residue was dried under a reduced pressure

Sources & evidence

ORD record
ord-96d6b978588e4fb7a1e2d245570e2579
Source dataset
uspto-grants-1988_04
Patent number
US04737497

Reaction notes

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