Methane → HCID 13588999, compound

Participants

Reaction Steps

A mixture of 13.7 g of the hydrochloride of Example 2 in 600 ml of methanol was subjected to hydrogen at 40° C. in the presence of 4.7 g of palladized charcoal and the mixture was then filtered. The filtrate was evaporated to dryness under reduced pressure at 40° C. and the residue was triturated in ether, filtered and dried at 20° to 25° C. under reduced pressure to obtain 7.9 g of 4-(1H-indol-4-yl)-4-piperidinol hydrochloride melting at 270° C.

Provenance & Evidence